Understandingthepathophysiologyofthebody’sresponsetohemorrhagehasledtoimprovementsinprehospitalcare,morerapidhemostasis,avoidanceofmassivecrystalloidresuscitation,andimprovedsurvival.
Hemorrhagicshockisaformofhypovolemicshockinwhichseverebloodlossleadstoinadequateoxygendeliveryatthecellularlevel.Ifhemorrhagecontinuesunchecked,deathquicklyfollows.Thecausesofhemorrhageresultinginshockvarywidelyandincludetrauma,maternalhemorrhage,
gastrointestinalhemorrhage,perioperativehemorrhage,andruptureofan
aneurysm.
Deathfromhemorrhagerepresentsasubstantialglobalproblem,withmorethan60,deathsperyearintheUnitedStatesandanestimated1.9milliondeathsperyearworldwide,1.5millionofwhichresultfromphysicaltrauma.Becausetraumaaffectsadisproportionatenumberofyoungpeople,these1.5milliondeathsresultinnearly75millionyearsoflifelost(Table1).Furthermore,thosewhosurvivetheinitialhemorrhagicinsulthavepoorfunctionalout北京治疗最好白癜风医院的偏方南宁最好的白癜风医院
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